| Income Tax Disclosure [Abstract] | Period [Axis] |
|---|
2016-01-01 - 2016-12-31 |
|---|
Income Tax Disclosure [Abstract] | |
Schedule of Components of Loss Before Income Taxes |
The following table presents domestic and foreign components of loss before provision for income taxes (in thousands):
|
|
|
Years ended December 31, |
|
|
|
|
2016 |
|
|
2015 |
|
|
2014 |
|
|
U.S. |
|
$ |
(96,498 |
) |
|
$ |
(47,235 |
) |
|
$ |
(25,006 |
) |
|
Foreign |
|
|
(18,024 |
) |
|
|
(218 |
) |
|
|
(398 |
) |
|
Loss before income taxes |
|
$ |
(114,522 |
) |
|
$ |
(47,453 |
) |
|
$ |
(25,404 |
) |
|
Schedule of Reconciliation of Income Tax Expense Computed Statutory Federal Income Tax and Financial Statements |
A reconciliation of income tax expense computed at the statutory federal income tax rate of 34% to income taxes as reflected in the financial statements is as follows (in thousands):
|
|
|
Years ended December 31, |
|
|
|
|
2016 |
|
|
2015 |
|
|
2014 |
|
|
Federal income tax expense at statutory rate |
|
$ |
(38,938 |
) |
|
$ |
(16,134 |
) |
|
$ |
(8,637 |
) |
|
Loss on extinguishment of related-party convertible notes |
|
|
— |
|
|
|
— |
|
|
|
69 |
|
|
Non-deductible foreign research expenses |
|
|
21 |
|
|
|
45 |
|
|
|
85 |
|
|
Non-deductible stock compensation |
|
|
1,356 |
|
|
|
1,418 |
|
|
|
161 |
|
|
Non-deductible expenses |
|
|
985 |
|
|
|
295 |
|
|
|
285 |
|
|
Goodwill impairment |
|
|
16,834 |
|
|
|
|
|
|
|
|
|
|
Research and development tax credits |
|
|
(326 |
) |
|
|
(910 |
) |
|
|
(304 |
) |
|
Change in valuation allowance |
|
|
16,062 |
|
|
|
15,277 |
|
|
|
8,349 |
|
|
Foreign rate differential |
|
|
3,231 |
|
|
|
9 |
|
|
|
(8 |
) |
|
Total tax expense (benefit) |
|
$ |
(775 |
) |
|
$ |
— |
|
|
$ |
— |
|
|
Schedule of Deferred Tax Assets |
The following table presents significant components of the Company’s deferred tax assets (in thousands):
|
|
|
As of December 31, |
|
|
|
|
2016 |
|
|
2015 |
|
|
2014 |
|
|
Deferred tax assets: |
|
|
|
|
|
|
|
|
|
|
|
|
|
Net operating loss carryforwards |
|
$ |
15,785 |
|
|
$ |
19,889 |
|
|
$ |
8,526 |
|
|
Accruals, reserve and other |
|
|
3,071 |
|
|
|
2,681 |
|
|
|
222 |
|
|
Stock-based compensation |
|
|
3,848 |
|
|
|
4,328 |
|
|
|
3,032 |
|
|
Tax credit carryforwards |
|
|
574 |
|
|
|
1,945 |
|
|
|
659 |
|
|
Property and equipment |
|
|
54 |
|
|
|
— |
|
|
|
— |
|
|
Intangibles |
|
|
68 |
|
|
|
45 |
|
|
|
24 |
|
|
Other |
|
|
— |
|
|
|
— |
|
|
|
24 |
|
|
Total deferred tax assets before valuation allowance |
|
|
23,400 |
|
|
|
28,888 |
|
|
|
12,487 |
|
|
Valuation allowance |
|
|
(23,400 |
) |
|
|
(28,839 |
) |
|
|
(12,457 |
) |
|
Total deferred tax assets |
|
|
— |
|
|
|
49 |
|
|
|
30 |
|
|
Deferred tax liabilities: |
|
|
|
|
|
|
|
|
|
|
|
|
|
Property and equipment |
|
|
— |
|
|
|
(49 |
) |
|
|
(30 |
) |
|
IPR&D |
|
|
(1,250 |
) |
|
|
— |
|
|
|
— |
|
|
Total deferred tax liabilities |
|
$ |
(1,250 |
) |
|
$ |
(49 |
) |
|
$ |
(30 |
) |
|
Net deferred tax assets |
|
$ |
— |
|
|
$ |
— |
|
|
$ |
— |
|
|
Schedule of Unrecognized Tax Benefits |
A reconciliation of the unrecognized tax benefits is as follows (in thousands):
|
|
|
Years ended December 31, |
|
|
|
|
2016 |
|
|
2015 |
|
|
2014 |
|
|
Unrecognized tax benefits as of the beginning of the year |
|
$ |
1,568 |
|
|
$ |
471 |
|
|
$ |
43 |
|
|
Increase (decrease) related to prior year tax provisions |
|
|
— |
|
|
|
172 |
|
|
|
272 |
|
|
Increase related to current year tax provisions |
|
|
589 |
|
|
|
925 |
|
|
|
156 |
|
|
Unrecognized tax benefits as of the end of the year |
|
$ |
2,157 |
|
|
$ |
1,568 |
|
|
$ |
471 |
|
|