Slicers (applies to each fact value in each table cell)

Reporting Entity [Axis]

0001054274 (http://www.sec.gov/CIK)

Accrued Liabilities, Current [Abstract]	Period [Axis]
	2016-01-01 - 2016-12-31
Accrued Liabilities, Current [Abstract]
Schedule of Accrued Liabilities [Table Text Block]	Accrued expenses and other current liabilities consist of the following (in thousands):       December 31,     December 31,       2016     2015                 Salaries, benefits and incentive compensation   $ 3,070     $ 2,118   Milestone payment to licensor     1,000       -   Professional fees     692       671   Royalty fees     197       52   Deferred revenue     181       92   Other     146       138   Total accrued expenses and other current liabilities   $ 5,286     $ 3,071