Entity information:
14.
Income Taxes
 
For each of the years ended
December
31,
2016,
2015
and
2014,
the Company recorded a provision for income taxes of
$0.5
million. The provision for income taxes for the years ended
December
31,
2016,
2015
and
2014,
primarily relates to accrued withholding taxes that would be due in connection with the payment of interest on intercompany loans. Other than the above mentioned provision for income taxes,
no
additional provision for income taxes has been made, net of the valuation allowance, due to cumulative losses since the commencement of operations.
 
The components of income (loss) before income taxes, loss from investments in affiliates and noncontrolling interest are as follows for the years ended
December
31,
2016,
2015
and
2014
(in thousands):
 
    Years Ended December 31,
    2016   2015   2014
United States   $
(101,210
)   $
(188,943
)   $
10,847
 
Foreign    
4,429
     
(24,457
)    
(5,275
)
Income (loss) before income taxes and loss from investments in affiliates   $
(96,781
)   $
(213,400
)   $
5,572
 
 
The components of the provision for income taxes are as follows for the years ended
December
31,
2016,
2015
and
2014
(in thousands):
 
    Years Ended December 31,
    2016   2015   2014
Current:                        
Federal   $
    $
    $
 
State    
     
     
 
Foreign    
553
     
468
     
495
 
Total current provision    
553
     
468
     
495
 
Deferred:                        
Federal    
     
     
 
State    
     
     
 
Foreign    
     
     
 
Total deferred provision    
     
     
 
Total provision for income taxes   $
553
    $
468
    $
495
 
 
A reconciliation between the statutory federal income tax and the Company’s effective tax rates as a percentage of income (loss) before income taxes is as follows:
 
    Years Ended December 31,
    2016   2015   2014
Statutory tax rate    
(34.0
)%    
(34.0
)%    
(34.0
)%
State tax rate, net of federal benefit    
0.0
%    
(0.3
)%    
23.3
%
Stock-based compensation    
%    
0.1
%    
(2.8
)%
Federal R&D credit    
(0.8
)%    
(0.6
)%    
31.0
%
Derivative liabilities    
1.4
%    
3.6
%    
541.5
%
Non-Deductible Interest    
5.0
%    
5.5
%    
0.0
%
Other    
(3.2
)%    
0.1
%    
(7.8
)%
Foreign losses    
0.5
%    
(1.2
)%    
32.3
%
Change in valuation allowance    
31.7
%    
27.1
%    
(592.4
)%
Effective income tax rate    
0.6
%    
0.3
%    
(8.9
)%
 
 
Temporary differences and carryforwards that gave rise to significant portions of deferred taxes are as follows (in thousands):
 
    December 31,
    2016   2015   2014
Net operating loss carryforwards   $
236,741
    $
207,241
    $
195,536
 
Fixed assets    
12,917
     
10,519
     
1,299
 
Research and development credits    
17,348
     
16,612
     
14,701
 
Foreign Tax Credit    
2,452
     
1,899
     
1,431
 
Accruals and reserves    
30,303
     
26,366
     
16,425
 
Stock-based compensation    
17,184
     
19,048
     
18,773
 
Capitalized start-up costs    
9,182
     
9,568
     
13,095
 
Capitalized research and development costs    
65,962
     
63,339
     
56,880
 
Other    
6,714
     
9,999
     
6,700
 
Total deferred tax assets    
398,803
     
364,591
     
324,840
 
Fixed assets    
     
     
 
Debt discount and derivative    
(11,936
)    
(4,402
)    
(12,517
)
Total deferred tax liabilities    
(11,936
)    
(4,402
)    
(12,517
)
Net deferred tax asset prior to valuation allowance    
386,867
     
360,189
     
312,323
 
Less: Valuation allowance    
(386,867
)    
(360,189
)    
(312,323
)
Net deferred tax assets (liabilities)   $
    $
    $
 
 
Recognition of deferred tax assets is appropriate when realization of such assets is more likely than not. Based upon the weight of available evidence, especially the uncertainties surrounding the realization of deferred tax assets through future taxable income, the Company believes it is more likely than not that the net deferred tax assets will
not
be fully realizable. Accordingly, the Company has provided a full valuation allowance against its net deferred tax assets as of
December
 
31,
2016,
2015
and
2014.
The valuation allowance increased by
$26.7
million,
$47.9
million, and
$28.3
million, during the years ended
December
31,
2016,
2015
and
2014,
respectively.
 
As of
December
31,
2016,
the Company had federal net operating loss carryforwards of approximately
$645.3
million, and state net operating loss carryforwards
$208.7
million, available to reduce future taxable income, if any. As of
December
31,
2016
approximately
$27.2
million, of the federal loss carryforwards and
$12.9
million of state net operating loss carryforwards, respectively, related to excess stock-based compensation, and accordingly no deferred tax asset is recognized for such amounts prior to the adoption of ASU
2016
-
09,
discussed above in the
Recent Accounting Pronouncements
section of Note
2,
“Summary of Significant Accounting Policies.” Any deferred tax asset recognized on adoption of ASU
2016
-
09
related to excess stock-based compensation, net of any applicable valuation allowance, will be recorded to retained earnings as of the date of adoption.
 
During the year ended
December
31,
2015,
unrecognized tax benefits of
$8.5
million were resolved in connection with the outcome of a California Supreme Court case, involving another taxpayer, that concluded on a methodology which follows that certain of the Company’s net operating losses cannot be sustained. The decision had no impact on the Company’s gross deferred tax assets as presented, as the Company’s deferred tax asset for net operating losses was previously reported, net of a reserve for this same item.
 
As of
December
31,
2016,
the Company had federal research and development credits of
$9.8
million and California research and development credit carryforwards of
$11.4
million.
 
The Tax Reform Act of
1986
(TRA) and similar state provisions limit the use of net operating loss and credit carryforwards in certain situations where equity transactions result in a change of ownership as defined by Internal Revenue Code Section
382.
In the event the Company has experienced an ownership change, as defined in the TRA, utilization of its federal and state net operating loss and credit carryforwards could be limited. If not utilized, the federal net operating loss carryforward begins expiring in
2025,
and the California net operating loss carryforward begins expiring in
2016.
The federal research and development credit carryforwards will expire starting in
2024
if not utilized. The California tax credits can be carried forward indefinitely.
 
A reconciliation of the beginning and ending amounts of unrecognized tax benefits is as follows:
 
Balance at December 31, 2013   $
6,080
 
Increases in tax positions for prior period    
4,736
 
Increases in tax positions during current period    
6,265
 
Balance at December 31, 2014   $
17,081
 
Decreases in tax positions for prior period    
(9,404
)
Increases in tax positions during current period    
957
 
Balance at December 31, 2015   $
8,634
 
Decreases in tax positions for prior period    
(314
)
Increases in tax positions during current period    
781
 
Balance at December 31, 2016    
9,101
 
 
The Company’s policy is to include interest and penalties related to unrecognized tax benefits within the provision for taxes. The Company determined that
no
accrual for interest and penalties was required as of
December
31,
2016,
December
31,
2015
or
December
31,
2014.
 
None
of the tax benefits, if recognized, would affect the effective income tax rate for any of the above years due to the valuation allowance that currently offsets deferred tax assets. The Company does
not
anticipate the total amount of unrecognized income tax benefits will significantly increase or decrease in the next
12
months.
 
The Company’s primary tax jurisdiction is the United States. For United States federal and state tax purposes, returns for tax years
2004
and forward remain open and subject to tax examination by the appropriate federal or state taxing authorities. Brazil tax years
2009
through the current remain open and subject to examination.
 
As of
December
 
31,
2016,
the US Internal Revenue Service (IRS) has completed its audit of the Company for tax year
2008
which concluded that there were
no
adjustments resulting from the audit. While the statutes are closed for tax year
2008,
the US federal tax carryforwards (net operating losses and tax credits)
may
be adjusted by the IRS in the year in which the carryforward is utilized.